“Milestone” achieved – cell rejuvenation restores eyesight to mice

Sturgeon-Scotland

Making the blind see again: What sounds like a biblical miracle, researchers are now at least able to do with mice. With the help of a rejuvenating cocktail made from proteins, they restore half of their visual acuity to the animals. Human beings could do that in two years. Scientists may have made a breakthrough in the treatment of age-related diseases: cell rejuvenation allowed them to restore eyesight in mice – a therapy that could be used in humans for glaucoma eye disease and other age-related diseases. This is the result of a study published in the specialist journal “Nature”. Study director David Sinclair from Harvard Medical School even hopes that the method can be used against dementia. Blood cells rejuvenated Researchers reverse the aging process The procedure provides the opportunity to effectively turn back time at the cellular level and help cells regain the ability to heal damage. “I’m excited to rejuvenate organs and tissues that fail with age and disease,” said Sinclair. He made the prospect of treating glaucoma, better known as glaucoma, in people in two years. Population on a shrinking course Germany is losing 20 million inhabitants The ability of cells to regenerate and repair themselves decreases rapidly with age. The researchers therefore modified a process that produces a certain type of stem cell. These cells are created by a cocktail of four proteins that help reprogramming a cell. To restore the cells to a youthful state, they injected mice with optic nerve damage with three of the four proteins in the cocktail. Tests showed “that half of the visual acuity lost by the increased intraocular pressure was restored”. Treatment in elderly mice with age-related poor eyesight showed similar promising results. After the cocktail was injected, the eyesight of the mice improved. Side effects did not occur within the academic year. Andrew Huberman, a neuroscientist at Stanford University who was not involved in the study, called the results “a milestone in this area”. These would have to be confirmed in further animal experiments before humans can be treated with them. But an era has dawned which proves that an understanding of neural development processes leads to the tools “to repair the aged or damaged brain”.

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